Visit the main HIFA website: www.hifa2015.org

Estimating the lost benefits of antiretroviral drug use in South Africa.

Citation: 
CITATION: Chigwedere P1, Seage GR 3rd, Gruskin S, Lee TH, Essex M. Estimating the lost benefits of antiretroviral drug use in South Africa. J Acquir Immune Defic Syndr. 2008 Dec 1;49(4):410-5.
Abstract / Summary: 
ABSTRACT: South Africa is one of the countries most severely affected by HIV/AIDS. At the peak of the epidemic, the government, going against consensus scientific opinion, argued that HIV was not the cause of AIDS and that antiretroviral (ARV) drugs were not useful for patients and declined to accept freely donated nevirapine and grants from the Global Fund. Using modeling, we compared the number of persons who received ARVs for treatment and prevention of mother-to-child HIV transmission between 2000 and 2005 with an alternative of what was reasonably feasible in the country during that period. More than 330,000 lives or approximately 2.2 million person-years were lost because a feasible and timely ARV treatment program was not implemented in South Africa. Thirty-five thousand babies were born with HIV resulting in 1.6 million person-years lost by not implementing a mother-to-child transmission prophylaxis program using nevirapine. The total lost benefits of ARVs are at least 3.8 million person-years for the period 2000-2005.   What has been learned from the above? How can such policymaking be prevented?   Equally, how did health policymakers deal with the situation in the years following the episode? How did the policy get overturned so that ARVs could be made more available? And how has South Africa managed subsequently to introduce health policymaking that is evidence-led?
WHO Regions and Countries: 
Users of healthcare information: 
Full text access?: 
Selected extracts: 

Coincidentally, a news article was published March 2016 under the title 'I never said HIV does not cause Aids - Mbeki. '"What I said is that 'a virus cannot cause a syndrome'," Mbeki said... The full article, including a link to further information on Mbeki's website, is available here: http://www.news24.com/SouthAfrica/News/i-never-said-hiv-does-not-cause-a...

Formal literature type: 
Journal title: 
Author(s): 

Chigwedere P1, Seage GR 3rd, Gruskin S, Lee TH, Essex M.

Year published: 
2008
Month published: 
N/A